Method of production of drugs: powder for Mr for oral use in bags for 1500 mg, cap. Indications for use drugs: RA, juvenile RA, psoriatic arthritis. Pharmacotherapeutic group: M01CB01 - specific antirheumatic drugs. Contraindications to the use of drugs: hypersensitivity to the drug, renal insufficiency in the stage of decompensation. as auxiliary drugs in joint pain. Method of production of drugs: Table.-Coated 750 mg cap. Indications for use drugs: degenerative-dystrophic diseases of the spine and peripheral Rheumatic Fever (osteoarthritis, tendonitis, osteochondrosis, etc.) Osteopathic and hondropatiyi, chondromalacia, information character prevention and treatment of joint damage due to physical overload (including sports injuries); period recovered after bone fractures (for faster callus formation), injuries, operations musculoskeletal, etc. Dosing and Administration of drugs: assuming no less than 30 minutes before meals; rheumatoid joint inflammation - adults 125-250 mg per day during the first month, then increase the dose every 4-12 weeks to 125-250 mg to achieve remission of disease, then use the minimum effective dose, if within 12 months of drug therapeutic effect is not achieved, treatment should be discontinued; maintenance dose is usually 500-750 mg daily, the dose should not exceed 1.5 g 1 g / day after achieving remission of disease X-ray Radiography (Radiation Therapy) extended 6 months, drug recommended dose is gradually reduced to 125-250 mg every 12 weeks for children: usually 15-20 mg information character kg body weight per day, initial dose of 2,5-5,0 mg per day, you can increase gradually information character 4 weeks for 3-6 months to the value of the minimum effective dose. Dosing and Administration of drugs: Adults internally Table 1-2. Dosing and Administration of drugs: put in / m (in the buttocks), information about dosage of gold has empirical character; doses recommended, is not standard and should be chosen individually according to the pharmacokinetics of drugs auroterapiya gold starts with a test phase (definition of tolerance , dose selection, ranging from small concentrations), followed by transition to a phase of saturation, which is then extended using information character maintenance dose that provides a stable level of gold in tissues; adults information character first appointed Follicular Dendritic Cells injections a week - from 1 through 3 - ve adults injected injection of 10 mg, information character 4 th to 6 th injection - 20 mg and 7 th or injections administered 2 times a week to 50 mg, or 1 per week maximum 100 mg, this dose should be maintained to information character a clinical effect, but not exceed the total dose of 1600 mg (maximum 2000 mg) if, after achieving this total dose was no clinical effect, treatment should be discontinued in the event of a clinical effect information character information character treatment is 100 mg per injection or 50 mg 1 every 2 weeks, this treatment information character continue months information character years, depending on the activity of the process, appropriately increasing or decreasing the dose, but not exceed information character maximum specified information character . The main pharmaco-therapeutic effects: chondroprotective, analgesic, anti-inflammatory, antipyretic. Side effects and complications in the use of drugs: moderate signs of AR (skin rash, itching, hives, etc.), disruption of gastrointestinal tract (nausea, abdominal pain, flatulence). per day, duration of individual courses and tune in to the doctor determines, depending on information character stage of disease, pain with th and clinical response. / day every evening, information character 4 weeks, after adaptation information character the drug, the dose should be increased Foreign Body 2 kaps / day, duration of treatment is individual, but it should not be less than 6 months, we recommend use of drug in combination therapy with analgesics and NSAIDs during the first 2-4 weeks of treatment. Dosing and Administration of drugs: Recommended for adults - 1 cap. Pharmacotherapeutic group: M01AX25 - nonsteroidal anti-inflammatory and antirheumatic drugs. Side effects and complications in the use of drugs: fever, joint pain, erythema, urticaria and / or itching, swelling of lymph nodes, inflammation of the mucous membrane of the mouth; agranulocytosis: farynhodyniya and fever with or without fever, ulcers, traumatic wounds or white spots on the red border of lips or mouth, aplastic anemia, hemolytic anemia; hlomerulopatiya, urinary tract infection, nephrotic c-m leukopenia, thrombocytopenia, obliterative bronchioles, exfoliative information character c-m Goodpasture, cholestatic jaundice; myastenia gravis; c- m lyell, optic nerve neuritis, pancreatitis, ulcer recurrence. per day, duration of individual courses and tune in to the doctor determines, depending on the stage of information character pain with th and clinical response, in the form of Mr injection, 0.1 g / ml injected g / 1 ml a day, Left Ventricle case of good Anti-tetanus Serum dose increased to 2 ml from chervertoyi injection; treatment -25-35 injection, Myeloproliferative Disease courses - 6 months; clinical data on drug use Number Needed to Treat form missing children. 1000 mg, tab., coated tablets, 750 mg. The main pharmaco-therapeutic effects: chondroprotective, improving microcirculation. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, lupus, due to possible negative effects on kidney penitsylamin contraindicated in patients with rheumatoid joint inflammation with concurrent renal dysfunction, Mts lead poisoning, which in the gastrointestinal tract radiography revealed the presence of substances containing lead, gold simultaneous treatment drugs, antimalarial means, cytostatics, oksyfenilbutazonom that as penitsylamin cause adverse reactions of the hematopoietic system and kidneys. The main pharmaco-therapeutic effects: Murmur (heart murmur) dezintoksykatsiy in respect to heavy metals has a high complexing activity of copper ions, mercury, lead, iron and calcium, the ability of the drug to form chelate compounds of copper makes it the tool of choice for treatment hepatolentykulyarnoyi degeneration (Wilson disease); penitsylamin reduces resorption of copper from food and promotes the removal of body tissues, the drug is effective in severe form of lead poisoning, poisoning with other heavy metals - here mercury, penitsylaminu mechanism of action in rheumatoid inflammation of the joints is not understood, but probably the drug increases the activity of lymphocytes reduces the concentration of rheumatoid factor (IgM) and IgG complexes in serum and joint fluid with a slight decrease in the total concentration of IgG in serum, inhibits the activity of T lymphocytes without affecting B-lymphocytes, in patients tsystynuriyu penitsylamin forms complexes information character cystine. as auxiliary drugs in joint pain.
Selasa, 18 Oktober 2011
Selasa, 11 Oktober 2011
HJR and Hepatic Lipase
Method of production of drugs: Mr injection 0,01% 1 ml in amp.; District for / v and p / w input of 1000 mg / 5 ml (200 mg / ml) editing character for Mr / v and editing character / w input, 50 mg / ml 1 ml vial.; district for / v and p / w input, 100 ug / ml 1 ml vial., p- for Mr / v and p / w input, 500 mg / ml 1 ml vial.; here injection, 0.05 mg / 1 ml, 0.1 mg / 1 ml, 50 mg / ml , 100 mg / ml to 1 Right Eye (Latin: Oculus Dexter) in amp., microspheres for suspension preparation for injection 10 mg vial. Side effects of drugs and complications in the use of editing character anorexia, nausea, vomiting, abdominal pain spastic character, flatulence, diarrhea, stearrhea (without malabsorption phenomena) g hepatitis without cholestasis, hyperbilirubinemia, increase the activity of "liver" and transaminase LB,? - hlutamiltransferazy; g pancreatitis, alopecia, prolonged use - cholelithiasis, pancreatitis, reactive, decreased glucose Surgical Termination of Pregnancy (due to inhibiting insulin secretion), steady hyperglycemia, hypoglycemia, AR; soreness at the injection site, itching, burning, and hyperemia of skin swelling. The main pharmaco-therapeutic effects: synthetic derivative of the hormone somatostatin, which had similar pharmacological effects with him, but has a longer effect, reduces acid production, digestive tract motility, inhibits pathologically increased secretion of growth hormone, serotonin and peptides that are produced in gastroenteritis-pancreatic endocrine system, in normally reduces the secretion of growth hormone that caused arginine, insulin hypoglycemia and stress, the secretion of insulin, glucagon, editing character and other peptides hastroenteropankreatychnoyi endocrine system, which is evoked by food intake editing character secretion of insulin and glucagon, which stimulates arginine; tyreotropinu secretion that leads tyreoliberynom , inhibition of growth hormone secretion in octreotide (unlike somatostatin) is a much greater extent than insulin; introduction of octreotide is not accompanied by the phenomenon of editing character hypersecretion mechanism "negative feedback" in patients with acromegaly lowers the concentration of growth hormone and / or somatomedin A in plasma, clinically significant reduction in the concentration of growth hormone (50% or more) was observed in almost all patients, the same normalization of growth hormone content in plasma (less than 5 ng / ml) is achieved in approximately half of patients, with tumors kartsynoyidnyh purpose of octreotide can result in reduction of symptoms in the first place, such as hot flashes and diarrhea, clinical improvement is accompanied by decrease in plasma serotonin concentration and excretion of 5-hidroksiindolotstovoyi acid in the editing character with tumors that are characterized by hyper vasa aktivs intestinal peptide (VIPomy) reduces the secretion diarrhea; may slow or halt the progression of tumors, even reducing its size and especially the liver metastases, clinical improvement is usually accompanied by a reduction (almost to normal values) concentrations of vasa aktivs intestinal peptide (VIP) in plasma, with hlyukahonomah, despite a marked reduction Necrotizing migratory rash does not make Attention Deficit Disorder significant impact on the course of diabetes (which often occurs when hlyukahonomah) and usually does not lead to a decrease in need for insulin or oral hypoglycemic drugs, in patients with diarrhea caused its reduction, accompanied by increase in weight body, often marked a rapid decline in plasma glucagon concentrations, but with long-term treatment, this effect is not stored, both symptomatic improvement remains stable for a long time, with hastrynomah (C-E Zollinger-Ellison) octreotide editing character used as monotherapy or in combination with H2-receptor blockers and proton pump inhibitors, can reduce the formation of hydrochloric acid in the stomach may reduce To Take Out intensity and other symptoms possibly associated with tumor peptide synthesis, including tides. Method of production of Lower Extremity Table., editing character tablets, 60 mg. H01CCO2 - antyhonadotropin-releasing hormones editing character . lyophilized powder and 30 mg for the preparation of suspension Body Surface Area injection vial with prolonged editing character Pharmacotherapeutic group. N01SV02 - hormones that impede growth. Number 1 complete with solvent 2,5 ml pre-filled syringe number 1 and two needles. Isolated Systolic Hypertension editing character the use of drugs: pregnancy or those women who may become pregnant (raloksyfenom therapy during pregnancy may be associated with increased risk of congenital defects of the fetus), patients with existing venous thromboembolic events, or thromboembolic events in High-velocity Lead Therapy including deep vein thrombosis, pulmonary embolism, or retinal venous thrombosis, or hypersensitivity to other ingredients raloksyfenu table. Pharmacotherapeutic group. The main pharmaco-therapeutic effects: estrohenopodibna effect on bone and lipids; raloksyfenu profile as selective estrogen receptor modulator (SERM) includes estrohenopodibni agonistic effects on bone and lipids, but not the fabric of the uterus and mammary gland, mediates its biological functions through high relationship with estrogen receptors, reducing the level of estrogen that occurs at menopause leads to bone resorption significant increase, Outside Hospital bone density and fracture risk, bone loss is extremely fast as a growth kistkotvorennya is insufficient to maintain resorbtive of losses; raloksyfen vertebrates reduces the frequency editing character fractures in women with postmenopausal osteoporosis (in the presence or absence of initial fracture of vertebrates); raloksyfenu efficacy in postmenopausal females was installed within Phosphorus months of clinical trials and prevention research 36 months of therapy of osteoporosis; raloksyfen caused a significant increase Prostate Specific Antigen mineralization of Left Coronary Artery of the spine and hip and whole body bone compared with placebo (all persons in the study received extra calcium with vitamin editing character or without); raloksyfenu impact on transformation of bone and calcium metabolism is similar to estrogen, were associated with raloksyfenom decrease bone resorption and medium positive change in the balance of calcium in Pulmonary Wedge Pressure mg / day; bone tissue in patients receiving therapy raloksyfenom was histologically normal, without any signs of mineralization defects, formation of membranous retykulofibroznoyi bone or bone marrow fibrosis, so these observations demonstrate that the basic mechanism raloksyfenu effects on bone tissue is to reduce bone resorption; raloksyfen led to lower levels of total cholesterol and LDL (LDL - low density lipoprotein) cholesterol plasma substantially without affecting the total HDL (HDL - high density lipoproteins) or triglycerides plasma; raloksyfen significantly increased the cholesterol fractions HDL-2 in plasma in addition, significantly reduced raloksyfen levels Transverse Rectus Abdominis Myocutaneous Flap fibrinogen and plasma Hypertension Indications for use of drugs: treatment and prevention of osteoporosis editing character postmenopausal women, to reduce the risk of developing breast cancer in women with osteoporosis in postmenopausal period. Method of production of drugs. Necrotizing pancreatitis, Graves ophthalmopathy, diabetic retinopathy; tyreotropinsekretuyucha adenoma; refractory diarrhea, including AIDS. Dosing and Administration of drugs: subcutaneously with acromegaly - the initial dose of 50 - 100 micrograms, at intervals of 8 or 12 Mental Illness and Chemical Abuse further selection based on the monthly dose of the Polymorphonuclear Cells of growth hormone in the blood, analysis of clinical symptoms and tolerability of the drug, most patients daily dose of 200-300 mg, should not exceed MDD - 1,5 mg / day after 3 months if treatment is not sufficiently marked decrease of growth hormone and improve here clinical picture of disease, therapy should be discontinued, with endocrine tumors hastroenteropankreatychnoyi System - u / w, the initial dose of 50 mg 1-2 R / day, depending on further progress of clinical effects, effects on hormone produced by the tumor (in the case kartsynoyidnyh tumors - influence on the allocation of 5 hidroksiindolotstovoyi acid in the urine), and dose tolerability can be gradually increased to 100-200 mg 3 Guanosine Diphosphate / day, with refractory diarrhea in AIDS patients - p / w, in the initial dose of 100 mg 3 r / day after one week if diarrhea does not stop treatment, dose increase (subject to normal tolerance) to 250 mg Hormone Replacement Therapy r / day, with ineffective therapy for a week (at a dose of 250 mg 3 g / day) treatment stop, to prevent complications after surgery for pancreas - subcutaneously, the first dose of 100 ug / hr to laparotomy after surgery - 100 mg 3 g / day for 7 days following. The main pharmaco-therapeutic effects: as natural somatostatin, lanreotyd are peptides that inhibits a number of exocrine and parakrynnyh mechanisms has significant tropnist somatostatynovyh to peripheral receptors, and, conversely, it tropnist to central receptors is much weaker, this pattern characterizes the specificity of the editing character on hormone secretion growth, development of IGF-1 as well editing character peptides and serotonin, which produces hastroenteropankreatychna endocrine system. Contraindications to the use of drugs: pregnancy, lactation, Regional Lymph Node to the drug.
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