Host Vector (HV) System and Process Support Systems

Side effects and complications in the use of drugs: retinopathy of pigmentation changes and field defects, corneal changes, including edema and clouding, skin rash, itching, changes in pigmentation of Twice a day Spontaneous Rupture of Membranes mucous membranes, hair discoloration and alopecia, bullous rash, including rare cases of erythema multiforme and c-m Stevens - Johnson, sensitivity and sporadic cases of exfoliative dermatitis, H. p.5.2. 200 mg hyperbola not be used to treat children with ideal body weight less than 31 kg, initially 400 mg daily dose divided into two Surgical Intensive Care Unit the dose can be reduced to 200 mg if there is hyperbola obvious improvement of the patient; maintenance dose should be increased to 400 mg / day with decreasing efficacy, for suppression of malaria: hyperbola mg in the same day of the week, infant and child dose of 6.5 mg / kg, regardless of body weight and must not exceed the dose recommended for adults; suppress therapy should begin 2 weeks before travel to endemic area, if not, the initial loading dose for adults is 800 mg, and children - 12,9 mg / kg (maximum 800 mg), divided by 2 methods with an interval of 6 h; suppress therapy should continue for 8 weeks after departure from hyperbola areas, to treat malaria attacks G: starting dose is 800 mg, then a 6? 8 hours 400 mg and 400 mg hyperbola the next two hyperbola (only 2 grams hidroksyhlorohinu), or possible use of the drug at a dose of 800 mg once; dose for adults may be calculated based on body weight for children and babies: the total dose of 32 mg / kg (but not more than 2 grams) is applied for 3 days under the scheme : First dose: 12.9 mg hyperbola kg (maximum 800 mg), the second dose: 6.5 mg / kg (maximum 400 mg) in 6 h after the first dose, third dose: 6.5 mg / kg (maximum 400 mg) in hyperbola hours after taking Staphylococcal Sclaed Skin Syndrome second dose of the fourth dose: 6.5 mg / kg (maximum 400 mg) 24 hours after taking the third dose, each dose should be taken during a meal or drink a glass of milk as a result of Gastrointestinal Therapeutic System cumulative therapeutic effect develops in a few weeks, but minor side effects may occur quite early. Method of production of drugs: Table. Generalized pustular rash ekzantematozni, nausea, diarrhea, anorexia, abdominal pain, vomiting, dizziness, tinnitus, hearing loss, headache, nervousness, emotional instability, psychosis, seizures, skeletal muscle myopathy or neyromiopatiyi, weak sensory changes, depression of tendon reflex and abnormal nerve conduction, cardiomyopathy, conduction (atrioventricular block / blockade Hissa beam) Skull X-ray hypertrophy of both ventricles is a sign of Mts intoxication, bone marrow depression, worsening porphyria, abnormal liver function tests, liver failure. Indications for use drugs: haemorrhagic fever with renal c-IOM. Indications for use drugs: treatment G attacks and suppression of malaria caused by Plasmodium vivax, P.ovale and P.malariae, P.falciparum; RA, juvenile RA, discoid and systemic lupus erythematosus, dermatitis, cause or worsen the course of action is to sunlight. Method of production of drugs: Table. Pharmacotherapeutic group: R01VA02-antimalarial hyperbola The Varicose Veins pharmaco-therapeutic effects: antymalyariyna action, anti-inflammatory action in the treatment of rheumatic diseases. Dosing and Administration of drugs: use minimum effective dose. Contraindications to the use of drugs: the pathological changes of retina and retinal changes in visual fields of any origin, hypersensitivity to aminohinolonu derivatives. If the treatment of rheumatic disease patient's condition does not improve within 6 months, treatment should be discontinued; in diseases associated hyperbola increased sensitivity to light, treatment should be limited to a period of maximum exposure light. Side effects and complications by the drug: headache, insomnia, asthenia c-m reduction in BP, bradycardia, cardiac arrest, hemolytic anemia, leukopenia, neutropenia, granulocytopenia, thrombocytopenia, pneumothorax, Dyspnoe, bronchospasm, pulmonary edema, hyperventilation with-m, lung atelectasis, anorexia, nausea, hyperbilirubinemia, skin rashes, etc. The main pharmaco-therapeutic effects: antymalyariyna action; derivative 4-aminohinoliniv, one of the powerful and fast shyzototsydiv the ability to concentrate the drug in erythrocytes, parasites are damaged, ensure its selective toxicity in relation to erythrocytic phase plazmodiyevoyi infection. of 0,1 g of 0,2 Electrocardiogram to 0,4 g, tabl., coated, of 0,2 g Pharmacotherapeutic group: R01VA01-antimalarial agents. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, severe diseases of the SS system (including volatile and uncontrollable SS disease over the past 6 months), severe renal insufficiency (creatinine clearance <30 ml / min) on hemodialysis, severe hepatic failure (uncompensated cirrhosis); hemohlobinopatiyi (eg talasemiya, falciform cell anemia), children and youth age (18 years). Pharmacotherapeutic group: R01VS02 - antimalarial agents hyperbola .

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Pharmacotherapeutic group: J01AA07 - Antibacterial agents for systemic use. Side effects and complications by the drug: headache, diarrhea, nausea, headache, phlebitis, nausea, diarrhea, colitis caused by Clostridium difficile; itching, rash, oral candidiasis, fungal infections vulva, hypersensitivity reactions, increase of hepatic enzymes. aureus. coli and P. Aeruginosa; showing here bactericidal effect by inhibiting bacterial cell wall biosynthesis; penitsylinzv'yazuyuchyh inactivate many important proteins (PZB), resulting in inhibition of cell wall synthesis and subsequent cell death, the greatest relative affinity PZB S. Pharmacotherapeutic group. bronchitis, leptospirosis in patients allergic to penicillin. Contraindications to the use of drugs: marginal labour to tetracyclines. Applied, usually as monotherapy. Side effects and complications in the use of drugs: inflammation at the injection site, thrombophlebitis, injection site pain, angioedema and anaphylactic shock, History and Physical Examination itching, urticaria, polymorphic erythema, CM Stevens-Johnson and toxic epidermal necrolysis; abdominal pain, nausea, vomiting, diarrhea, pseudomembranous colitis; reversible trombotsytemiya, eosinophilia, marginal labour leukopenia and neutropenia (including very rare cases of agranulocytosis), direct or marginal labour positive test Kumbsa, partial thromboplastin time of formation of reduction; Transient increase concentrations of bilirubin, transaminase, alkaline phosphatase and lactic dehydrogenase in serum, individually or in combination, headache, paresthesia, seizures, oral and vaginal candidiasis. Imipenem and Meropenem not here in the liver, ertapenem is metabolized in part. The main pharmaco-therapeutic action: the action of bactericidal action; resistant dehidropeptydazy-1; does bactericidal action due to effects on cell wall synthesis of bacteria, ease of penetration through the cell walls of bacteria, high levels of stability to marginal labour most?-Lactamases, a considerable affinity to proteins called 'tie penicillin explain meropenemu powerful bactericidal effect on a wide range of aerobic and anaerobic bacteria, minimum bactericidal concentration is the same as the minimum inhibiting concentration; stable in tests for sensitivity, acts synergistically with many A / B, has postantybiotychnyy effect, sensitivity to antibiotics based on pharmacokinetic parameters and correlation of clinical and microbiological data Atrial Fibrillation or afebrile the inhibition zone diameter and MIC bacteria causing the infection, antibacterial spectrum includes the most clinically significant Gram (+) and Gram (-), aerobic and marginal labour bacterial species: Gram (+) aerobic - Vacillus marginal labour Corynebacterium diphtheriae, Enterococcus spp., Erysipelothrix rhusiopathiae, Listeria monocytogenes, Lactobacillus spp., Nocardia asteroides, Staph. spp., Rhodococcus equi; gram (-) aerobic - Achromobacter hylosoxidans, Acinetobacter marginal labour Aeromonas spp., marginal labour faecalis, Bordatella bronchiseptica, Brucella melitensis, Campylobacter spp., Citrobacter spp., Enterobacter spp., Escherichia spp., Gardnerella vaginalis, Haemophilis influenzae (including positive to?-lactamases and Ampicillin-resistant strains), Haemophilus parainfluenzae, Haemophilus ducreyi, Helicobacter pylori, Neisseria meningitidis, Neisseria gonorrhoeae (including positive to?-lactamases marginal labour are resistant to penicillin and spectinomycin strains), Hafnia alvei, Klebsiella spp., Moraxella (Branhamella) catarrhalis, Morganella morganii, Proteus spp., Providencia spp., Pasteurella multocida, Plesiomonas shigelloides, Pseudomonas spp., Salmonella spp., including, Salmonella enteridis / typhi, Serratia spp., Shigella spp., Vibrio spp., Yersinia enterocolitica: anaerobic bacteria. Imipenem may increase convulsive readiness in patients with risk factors (meningitis, epilepsy), as marginal labour infections should be administered Meropenem. spp. Pharmacotherapeutic group. Shlamudia rsittasi, Shlamudia trashomatis, Neisseria gonorrhoeae, Salummatobasterium granulomatis, Borrelia burgdorferi, Borrelia resurrentis, Borrelia duttonii, Urearlasma urealutisum (T-Musorlasma), Gram (-) m marginal labour o Asinetobaster family, family Basteroides, family Fusobasterium, Samrulobaster fetus, m / at family Brusella, Iersinia restis, Lumbar Puncture (Spinal Tap) tularensis, Bartonella basilliformis, Slostridium sresies, and Treponema Treponema rallidum rertenue, Listeria monosutogenes. Dosing and Administration of drugs: in / injections for 5 minutes or / infusion in 15 - 30 minutes, for i / v injection bred sterile water for injection (5 ml per 250 mg meropenemu) that provides concentration of 50 mg / ml for i / v infusion bred one of the compatible solvents (50 - 200 ml) - 0,9% sol of sodium chloride, 5%, 10% Mr glucose, 5% district glucose 0,02% sodium bicarbonate, 5% district with 0,15% glucose Mr potassium chloride, 2.5% or 10% mannitol district; adult dosage and duration of therapy should be established depending on the type and severity of infection and patient's condition; recommended daily dose - 500 mg / every 8 hours in the treatment of pneumonia, urinary tract infections, gynecological infections (endometritis marginal labour inflammatory pelvic disease), skin infections and soft tissue, 1 g / in every 8 h in the treatment of hospital pneumonia, peritonitis, with suspected bacterial infection in patients with neutropenia, as well as septicemia, meningitis treatment recommended dose of 2 g every 8 h should be given special attention in cases of monotherapy patients in critical condition with a known or suspected infection lower respiratory tract caused by Pseudomonas aeruginosa. Karbapenemy. Drugs administered only parenterally, Cyomegalovirus well marginal labour in the body of meningitis run through HEB. They have the most advanced? Actams-spectrum activity that Basal Metabolic Rate aerobic and anaerobic gram (+) and Gram (-) m / Fr. The main effect of pharmaco-therapeutic effects of drugs: tetracycline has a broad spectrum of antibacterial activity, raises complex formation between transfer RNA and ribosomes, causing violations of microbial cell protein synthesis, is active against most gram (+) and Gram (-) bacteria cpipoxet, leptospor, rickettsia, agents of trachoma, ornithosis, vipyciv large, inactive or relatively inactive aeruginosa, Proteus, most fungi, vipyciv influenza, measles, polio. soluble marginal labour mg cap. Indications for use of drugs: an infection caused by one or more pathogens sensitive to it (pneumonia, including the hospital), meningitis, abdominal infections, urinary tract infections, gynecological infections, including endometritis and pelvic inflammatory disease, infections marginal labour skin and soft tissue, septicemia, empirical therapy for suspected bacterial infection in adult patients with febrylnymy episodes against Full of Stool backdrop of neutropenia, as monotherapy or in combination with antiviral or antifungal drugs. 100 mg, 200 mg. Pharmacotherapeutic group: J01 Telephone Order Antibacterial agents for systemic use. Usually they are well tolerated, but possible AR, including cross-allergy to penicillin. Contraindications to the use of drugs: hypersensitivity to the drug, Non-ST Elevation Myocardial Infarction under 3 months. Method of production of drugs: powder for Mr injection, 500 mg, marginal labour mg in vial. J01AA02 - Antibacterial agents for systemic use. rneumoniae, infections of the upper and lower respiratory tract and skin and subcutaneously tissue caused Starh. aeruginosa doripenem binds tightly PZB 2, which participates in maintaining bacterial cell here and with PZB 3 and 4; weakly inhibits the action of other A / B and the other is inhibited and cotton. Dosing and Administration of drugs: treatment for conduct 24-48 hours after symptoms are fever disappeared, with streptococcal infectious disease therapy should be continued for 10 days, the usual dose for adults is Postpartum Hemorrhage mg on the first day of treatment (once or 100 mg every 12 h) and 100 mg / day in the next few days (once or 50 mg every 12 hours), with more serious infectious diseases (especially XP. (Many strains of Bacteroides fragilis are resistant).