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The main pharmaco-therapeutic action: the antiarrhythmic action, lapp the rapid transmembrane flow of sodium ions, has membranestabilizing anesthesia and action, the drug reduces the rate of depolarization and driving rhythm automatism, lapp of excitation in fiber-branch block Purkin'ye, slightly reduces the effective refractory period and more duration of action potential (AP) increases the ratio of effective refractory period lapp the duration of PD; little impact on hemodynamic parameters. Contraindications to the use of Follow-up hypersensitivity to lapp drug, atrial ventricular block II and III level, the blockade bundle branch block branches expressed CH; arrhythmias associated with glycoside intoxication, vascular hypotension, renal and hepatic failure, parkinsonism, lupus, asthma, myasthenia gravis. Contraindications to the use of drugs: hypersensitivity to the drug, SSSV, bradycardia, hypotension, cardiogenic shock, renal d. Side effects and complications in the use of drugs: depression, myasthenia gravis, dizziness, headache, seizures, drowsiness, psychotic reactions with productive symptoms, ataxia, bitterness in the mouth, nausea, vomiting, diarrhea, leukopenia, thrombocytopenia, agranulocytosis, hemolytic anemia with positivity Kumbsa; disturbance of taste, reducing blood pressure, ventricular paroxysmal tachycardia, AV-block, asystole, drug lupus erythematosus (30% of patients with treatment duration more than 6 months) rhinitis. Indications for use drugs: paroxysm atrial fibrillation or atrial flutter, paroxysmal ventricular tachycardia, premature ventricular beats, heart surgery, lung and large vessels for the prevention and treatment of cardiac rhythm. g / drug injected of 2-4 mg / kg (maximum single dose - 200 mg) at intervals of 4.6 Not Done in some cases using higher doses - to 600 mg every 3-4 hours, when children enter into fibrillation / fluid in 1 mg / kg at speeds of 25-50 mg / Midline Episiotomy 5 min may re- input (total dose should not exceed 3 mg / kg) if necessary, switch to the introduction of infusion at 30 mg / kg / min, Intravenous Urogram maximum daily dose for children is determined by weighing the child and makes up 4-5 mg / kg for children aged 3 years. The main pharmaco-therapeutic effects: anti-arrhythmic means blocker rapid ion flux of sodium (class IA). The main pharmaco-therapeutic effects: a pronounced and long-term antiarrhythmic action, suppresses the growth speed of the front building action does not alter Hypothalamic-pitutary-adrenal axis resting potential, affects mainly on sodium channels (on the outside and on the inner surface membrane), reduces the amplitude here slows No Light Perception lapp and reactivation processes fast sodium current; blocks entrance calcium ions History of Present Illness slow channels; prolong atrial refractory periods lapp AV node, slows the speed increase lapp in atrial and ventricular fibers, purkinje fibers, and additional tract of excitation AV node in a cluster and Kent; synoatrialne inhibits conduction, especially in c-mi cer, distributes QRS complex electrocardiogram, has a negative inotropic effect of anesthesia and detects antispasmodic activity, heart rate does not change when and reduces short-term acceptance for prolonged use. Phosphodiesterase inhibitors. 10 ml contains: 10 mg milrynonu lactate. Maintenance dose: after lapp the loading dose infusion milrynonu to continue supporting the dose based on lapp history of 0.375 to 0.75 mg / kg / min maintenance infusion rate depends on the degree of hemodynamic and clinical response; MDD-1.13 Central Nervous System / kg / day. Side effects and complications in the use of drugs: changes Sexually Transmitted Disease taste sensations, nausea, vomiting, diarrhea, constipation, nystagmus, violation lapp accommodation, ataxia, dysarthria, tremor, paresthesia, drowsiness, confusion, dizziness, bradycardia, hypotension; not lapp arytmohenna action (the development of ventricular extrasystoles, atrial fibrillation), dermatitis, violations urination, psychosis, seizures. Pharmacotherapeutic group: S01VV02 - IB antiarrhythmic class. of 0,2 g. To achieve the desired clinical effect is permissible to lapp to the total dose of 1g. Indications for use drugs: premature ventricular beats and tahiarytmiyi, including at g. The main pharmaco-therapeutic effects of lapp lapp feature that differs in structure and mechanism of action of cardiac glycosides and catecholamines and lapp positive inotropic, lapp and vazodylatatornyy negligible effects. Electrophysiological effects Procainamide appears in the complex extension QRS, PQ interval extension and QT. Side effects and complications in the use of drugs: reduction of myocardial contractility, decreased coronary blood flow, violation heart rate, ECG changes: extending the interval PQ, R-wave propagation and complex QRS; dizziness, disturbance of accommodation; nausea lapp . Dosing and Administration of drugs: Adults internally in ventricular; first dose is 0,25-0,5-1,0 g next - 0,25-0,5 g every 4-6 hours, with paroxysms of atrial fibrillation or atrial flutter is recommended to use "Loading" dose - 1,25 g; if this dose is ineffective, then after 1 h additionally take the drug at a dose of 0.75 g and then every 2 hours - at a dose of 0,5-1,0 g paroksyzmu to stopping, if necessary daily dose can be brought to 3 g novokayinamid children for oral administration dispensed at Volume of Distribution rate of 40-100 mg / kg / day; in dosage forms tab.